A Case of Prader-Willi Syndrome with Obstructive Sleep Apnea

Background: Prader-Willi syndrome (PWS) is a genetic disease caused due to defect in DNA methylation within the Prader-Willi region (PWCR) at 15q11q13. A young female presenting with complaints of sleep disturbance, burning micturition, and pain in abdomen is a case in point. Patient was subjected to polysomnography and was diagnosed as Obstructive sleep apnea (OSA). Result: The relationship between Prader-willi syndrome and obstructive sleep apnea is established and hence monitoring of the patients of PWS is of significance in patients of OSA. Keywords: Genetic disorder, Obstructive sleep apnea, Prader-Willi syndrome, Polysomnography. Rishikesh Balasaheb Deshmukh, Harshita Rani, Amit Srivastava, Asna Khan, Krishna Bihari Gupta Department of Respiratory Medicine, Era Lucknow Medical college and hospital, Era university, Lucknow, UP, India

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