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Volume-12 Number-2, 2025 / Original Article

Prevalence of Allergic Bronchopulmonary Aspergillosis in Bronchial Asthma

Author:

Harshita Rani
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Rajendra Prasad
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Rishabh Kacker
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Asna Khan
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Rachit Sharma
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Amit Srivastava
Department of Respiratory Medicine, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India

Abstract:

Background: The exact prevalence among patients of bronchial Asthma for Allergic bronchopulmonary Aspergillosis(ABPA) is yet unknown. This study was done to estimate the prevalene of ABPA in patients of Bronchial Asthma

Methods: A total of 140 Bronchial asthma Patients, age ≥12yrs, diagnosed based on symptoms and spirometry were included in the study. All the patients were subsequently subjected to skin prick test for aspergillus fumigatus. Patients with positive skin prick test were subjected to further diagnostic work-up for ABPA. Confirmation of ABPA was done as per Rosenberg-Patterson criteria.

Result: The 140 bronchial asthma patients, Aspergillus Hypersensitivity was seen in 40 (28.6%) cases. IgE/IgG positivity was seen in 16 (11.4%) cases. As per SPT criteria, a total of 40 (28.6%) cases had score 2+ or above and were considered to be positive. Among these, maximum (n=24; 17.1%) had score 2+, 11 (7.9%) had score 3+ and 5 (3.6%) had score 4+. As per Rosenberg criteria a total of 16 (11.4%) cases were identified as ABPA.

Conclusion: There is a high prevalence of ABPA in asthma patients, underscoring the need for screening all asthmatic patients for ABPA.