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Volume-12 Number-1, 2025 / Review Article

Gut Microbiota and Their Role in Mental Health: A Review

Author:

Bishouno Bhowmick

Pharmacology & GP, American University of Barbados School of Medicine, Wildey, Bridgetown, Saint Michael, BB11100, Barbados

Danial Saeed

American University of Barbados School of Medicine, Wildey, Bridgetown, Saint Michael, BB11100, Barbados

Emilie Isabelle Weinberg

American University of Barbados School of Medicine, Wildey, Bridgetown, Saint Michael, BB11100, Barbados

Phebe Samuel

American University of Barbados School of Medicine, Wildey, Bridgetown, Saint Michael, BB11100, Barbados

Sarah Qidwai

Era college of pharmacy, Era University, Lucknow, U.P. India

Pushpendra D Pratap

Department of Biochemistry, Era college of pharmacy, Era University, Lucknow, U.P. India

Abstract:

Background: Current findings shown the microbiota, which has been found in human gut play various important role in many areas of health, including psychological to mental health. Dietary changes, lifestyle, probiotics, prebiotics, and some other factors directly inflected gut microbiota and its influence on mental health

Objective: Recent research has shown that direct communication between the digestive tract biota and the brain, known as commonly the "gut-brain axis".

Methods: A literature review was conducted to this mystery that how they affect each other. In this article, the search was based on the title and keywords such as mental health “microbiota stress, and depression, used on various websites, such as PubMed, Google Scholar, Research Gate, and Science Direct.

Results: The populations of microorganisms in the intestines affect mental and neurological activities. The gut microbiota, directly affect the mental health issues including schizophrenia, anxiety, depression, and autism spectrum disorder.

Conclusion: So for future prospect neurological experts gut microbiota will be important tools for diagnostic and therapeutic agent.