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Volume-12 Number-1, 2025 / Case Report

A Rare Case of Occipital Region Bony Calvarial Primary Osteosarcoma

Author:
Ruvy Verma
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Sumaiya Irfan
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Noorin Zaidi
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Nirupma Lal
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Md Ibrahim
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Mehnaz Khan
Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, UP, India
Abstract:
Rationale: Primary osteosarcoma of calvarium is considered one of the rarest neoplasm of skull and accounts for 1 to 3% of all skull neoplasms. It is an aggressive bone neoplasm and is characterized by presence of spindle cell leading to a generally poor prognosis.
Case report: A female patient aged appox 55-years came to our neurosurgery outpatient department having complain of progressively enlarging mass in occipital region of her skull. MRI revealed a lytic, expansile soft tissue lesion involving the occipital bone which was excised surgically and tissue was sent for histopathology which confirmed the final outcome as osteosarcoma of skull. Decompression surgery was done to alleviate symptoms.
Conclusion: Primary calvarial osteosarcoma is considered as one of the rarest neoplasm of skull, emphasizing need for prompt identification and accurate diagnosis to improve patient outcome. Clinician must be vigilant in recognizing this condition to facilitate timely intervention. A comprehensive treatment approach involving surgical resection followed by chemoradiation has been shown to yield optimal results.
Keywords:
Decompression Surgery, Occipital Region Bony Calvarial, Spindle Cells

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Copyright (c) 2026 Era's Journal of Medical Research

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Download PDF View in DOI 10.24041/ejmr.2025.16