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Volume-12 Number-1, 2025 / Review Articles

Herbal Medicines: An Extensive Analysis of Polyherbal Treatments for Metabolic Syndrome

Background: Diabetes and Heart disease are markedly elevated in individuals with metabolic syndrome, a group of disorders that includes obesity, hypertension, dyslipidemia, and insulin resistance. Using several pharmacological drugs in conventional therapies can have unfavourable side effects and low long-term effectiveness. Aim: The study aims to thoroughly examine the history, main components, methods of action, clinical effectiveness, safety profiles, and prospects for the future of polyherbal therapies for metabolic syndrome. Method: This review was carried out using Google Scholar as a secondary resource and databases including CINAHL, PubMed, Web of Science, and Scopus. Various polyherbal combinations were investigated for their efficacy in treating metabolic syndrome in both animal and human research, and they were taxonomically categorized. Result: High-quality data supported the efficacy of many polyherbal formulations, which dramatically improved multiple metabolic syndrome criteria, including insulin sensitivity, lipid profiles, and inflammation. Significant results from clinical investigations included better lipid profiles, decreased waist circumference, and enhanced glycemic management. Conclusion: These results highlight the potential of polyherbal formulations as an additional and perhaps more durable treatment option for metabolic syndrome, presenting an integrated and holistic approach to the condition. Keywords: Herbal medicine, Metabolic syndrome, Natural remedies, Phytotherapy, Polyherbal formulations. Vivek Ranjan Patel1, Akshay Kumar Gupta2, Jyoti Dwivedi1, Utkarsh Singh Tomar1, Aparna Misra1 1Department of Biochemistry, Era’s Lucknow Medical College & Hospital, Era University, Lucknow, UP, India 2Department of Biochemistry, Lucknow University, Lucknow, UP, India

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